IMGT Repertoire (IG and TR)

Alignment of alleles: house mouse (Mus musculus) TRAV14-2, TRAV14D-2 and TRAV14N-2

When several alleles are shown, the nucleotide mutations and amino acid changes for a given codon are indicated in red letters. These polymorphic mutations are reported in Tables of alleles.
Dashes indicate identical nucleotides. Dots indicate gaps according to the IMGT unique numbering. Blanks indicate partial sequences (blanks at the 5' and/or 3' end).
Dots indicate gaps according to the IMGT unique numbering.
Blanks at the 5' and/or 3' end indicate partial sequences.
Asterisk (*) in the sequence indicate a STOP-CODON.
Letters in red correspond to amino acids which are polymorphic in the other alleles.
Colours are according to Color menu for mutations, Color menu for sequence alignments and Color menu for splicing types.
The nucleotide (s) in bold and colored in purple (splicing frame 1) or green (splicing frame 2) from the DONOR splice site are added at the beginning of the following exon in order to obtain and to complete the first CODON of the DOMAIN or REGION resulting from the splicing site. These first CODONs are in bold and colored in purple (splicing frame 1) or green (splicing frame 2)
N (Asn, asparagine) of potential N-glycosylation sites (NXS/T, where X is different from P), (N-linked glycosylation) is shown in green
Clicking on the allele name gives access to the IMGT/GENE-DB.
Clicking on the accession number gives access to the IMGT/LIGM-DB.
                                                                                                                                
                                                
                                                 1   2   3   4   5   6   7   8   8A  9   10  11  12  13  14  15  16  17  18  19 
                                                 Q   Q   Q   V   R   Q   S   P       Q   S   L   T   V   W   E   G   E   T   A  
  L77148     TRAV14-2*01  F   V-REGION gDNA     cag cag cag gtg aga caa agt ccc ... caa tct ctg aca gtc tgg gaa gga gag aca gca 

                                                                                                                             T  
  U04312     TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --c a-- 

                                                                                                                             T  
  AC005402   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --c a-- 

                                                                                                                             T  
  AE007512   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --c a-- 

                                                                                                                                
  AC161460   TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  L77153     TRAV14-2*02  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14-2*02  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  M88352     TRAV14D-2*02 (F) V-REGION cDNA                                                                                     

                                                                                                                                
  U04625     TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC003997   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AE008685   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC163653   TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- 



                                                                            ___________________CDR1-IMGT____________________    
                                                
                                                 20  21  22  23  24  25  26  27  28  29  30  31  32  33  34  35  36  37  38  39 
                                                 I   L   N   C   S   Y   E   D   S   T                           F   D   Y   F  
  L77148     TRAV14-2*01  F   V-REGION gDNA     att ctg aac tgc agt tat gag gac agc act ... ... ... ... ... ... ttt gac tac ttc 

                                                                                                                                
  U04312     TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AC005402   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AC161460   TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  L77153     TRAV14-2*02  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14-2*02  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  M88352     TRAV14D-2*02 (F) V-REGION cDNA                                   - --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  U04625     TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AC003997   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AE008685   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  AC163653   TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- ... ... ... ... ... ... --- --- --- --- 



                                                                                                                _______________C
                                                
                                                 40  41  42  43  44  45  46  47  48  49  50  51  52  53  54  55  56  57  58  59 
                                                 P   W   Y   W   Q   F   P   R   E   S   P   A   L   L   I   A   I   R   P   V  
  L77148     TRAV14-2*01  F   V-REGION gDNA     cca tgg tac tgg cag ttc cct agg gaa agc cct gca ctc ctg ata gcc ata cgt cca gtg 

                                                             R               G   K                                   S   L      
  U04312     TRAV14D-2*01 F   V-REGION gDNA     --- --- --- c-- --- --- --- g-- a-- --- --- --- --- --- --- --- --- a-- ttg --- 

                                                             R               G   K                                   S   L      
  AC005402   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- c-- --- --- --- g-- a-- --- --- --- --- --- --- --- --- a-- ttg --- 

                                                             R               G   K                                   S   L      
  AE007512   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- c-- --- --- --- g-- a-- --- --- --- --- --- --- --- --- a-- ttg --- 

                                                                                                                                
  AC161460   TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                             H               G                                                  
  L77153     TRAV14-2*02  F   V-REGION gDNA     --- --- --- cat --- --- --- g-- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                             H               G                                                  
  IMGT000082 TRAV14-2*02  F   V-REGION gDNA     --- --- --- cat --- --- --- g-- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                             R                                                       S   L      
  M88352     TRAV14D-2*02 (F) V-REGION cDNA     --- --- --- c-- --- --- --- --- --- --- --- --- --- --- --- --- --- a-- ttg --- 

                                                             R   L           G                                                  
  U04625     TRAV14-2*03  F   V-REGION gDNA     --- --- --- c-t -t- --- --- g-- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                             R   L           G                                                  
  AC003997   TRAV14-2*03  F   V-REGION gDNA     --- --- --- c-t -t- --- --- g-- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                             R   L           G                                                  
  AE007512   TRAV14-2*03  F   V-REGION gDNA     --- --- --- c-t -t- --- --- g-- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                             R   L           G                                                  
  AE008685   TRAV14-2*03  F   V-REGION gDNA     --- --- --- c-t -t- --- --- g-- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC163653   TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                                DR2-IMGT________________                                                        
                                                
                                                 60  61  62  63  64  65  66  67  68  69  70  71  72  73  74  75  76  77  78  79 
                                                             S   N   K   K   E   D                       G   R   F   T   I   F  
  L77148     TRAV14-2*01  F   V-REGION gDNA     ... ... ... tcc aat aaa aag gaa gat ... ... ... ... ... gga cga ttc aca atc ttc 

                                                                                                                                
  U04312     TRAV14D-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AC005402   TRAV14D-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14D-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AC161460   TRAV14N-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14N-2*01 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  L77153     TRAV14-2*02  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14-2*02  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  M88352     TRAV14D-2*02 (F) V-REGION cDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  U04625     TRAV14-2*03  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AC003997   TRAV14-2*03  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14-2*03  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AE008685   TRAV14-2*03  F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  AC163653   TRAV14D-2*03 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14D-2*03 F   V-REGION gDNA     ... ... ... --- --- --- --- --- --- ... ... ... ... ... --- --- --- --- --- --- 



                                                                                                                                
                                                
                                                 80  81  82  83  84 84A  85  86  87  88  89  90  91  92  93  94  95  96  97  98 
                                                 F   N   K   R   E       K   K   L   S   L   H   I   T   D   S   Q   P   G   D  
  L77148     TRAV14-2*01  F   V-REGION gDNA     ttc aat aaa agg gag ... aaa aag ctc tcc ttg cac atc aca gac tct cag cct gga gac 

                                                                                                                                
  U04312     TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC005402   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14D-2*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC161460   TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                 F                   A                          
  L77153     TRAV14-2*02  F   V-REGION gDNA     --- --- --- --- --- ... --- --- t-- --- --- --- --- g-- --- --- --- --- --- --- 

                                                                                 F                   A                          
  IMGT000082 TRAV14-2*02  F   V-REGION gDNA     --- --- --- --- --- ... --- --- t-- --- --- --- --- g-- --- --- --- --- --- --- 

                                                                                                                                
  M88352     TRAV14D-2*02 (F) V-REGION cDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  U04625     TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC003997   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AE007512   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AE008685   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  AC163653   TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 

                                                                                                                                
  IMGT000082 TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- ... --- --- --- --- --- --- --- --- --- --- --- --- --- --- 



                                                                        ___CDR3-IMGT____
                                                
                                                 99 100 101 102 103 104 105 106 107 
                                                 S   A   T   Y   F   C   A   A   S  
  L77148     TRAV14-2*01  F   V-REGION gDNA     tca gct acc tac ttc tgt gca gca agt g

                                                                                    
  U04312     TRAV14D-2*01 F   V-REGION gDNA     --- --c --- --- --- --- --- --- --- -

                                                                                    
  AC005402   TRAV14D-2*01 F   V-REGION gDNA     --- --c --- --- --- --- --- --- --- -

                                                                                    
  AE007512   TRAV14D-2*01 F   V-REGION gDNA     --- --c --- --- --- --- --- --- --- -

                                                                                    
  AC161460   TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  IMGT000082 TRAV14N-2*01 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  L77153     TRAV14-2*02  F   V-REGION gDNA     --- --c --- --- --- --- --- --- --- -

                                                                                    
  IMGT000082 TRAV14-2*02  F   V-REGION gDNA     --- --c --- --- --- --- --- --- --- -

                                                                                    
  M88352     TRAV14D-2*02 (F) V-REGION cDNA     --- --c --- --- --- --- --- --- --- -

                                                                                    
  U04625     TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  AC003997   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  AE007512   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  AE008685   TRAV14-2*03  F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  AC163653   TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -

                                                                                    
  IMGT000082 TRAV14D-2*03 F   V-REGION gDNA     --- --- --- --- --- --- --- --- --- -
This alignment of allele is generated by IMGT/OutilAllele (Mehdi Yousfi, Chantal Ginestoux, Perrine Pégorier and Patrice Duroux).
Created:: 05/09/2022
Last updated:: 22/09/2023
Authors:: Guilhem Zeitoun